Code: PN-III-P2-2.1-PED-2019-3013, Contract no. 310PED/2020
Acronim: GreenTechMembr
Project leader: Dr. Anca Filimon
Contract Authority: UEFISCDI
Contractor: ICMPP
Period: 03.09.2020-29.07.2022.

https://icmpp.ro/greentechmembr/

The GreenTechMembr project addresses one of the big problems facing the society on the water pollution and aims at developing a new "green" technology for water treatment able to overcome the disadvantages of conventional technologies and to offer numerous advantages (minimum energy consumption, high selectivity, technical feasibility and low volume of waste), thus representing a "green", compact and economical alternative system.

Code: PN-II-ID-PCE-2011-3-0937/2011,  Contract no. 302/5.10.2011. 
Project director: Dr. Silvia Ioan
Contractor: ICMPP
Period: 2011-2014

The project theme was focused on the development of complex systems containing new imide type polymers based on flexible and/or rigid alicyclic monomers with potential applications in advanced technologies as alignment layers for liquid crystals (LC ALs), dielectric and/or surface-related materials.

Code: PN-II-RU-TE-2012-3-0143/2013. Contract no. 62/30.04.2013.
Project director: Dr. Anca Filimon
Contractor: ICMPP
Period: 2013 - 2016

Project was aimed to achieve new composites/blends - functionalized polysulfones/natural polymer and functionalized polysulfones/synthetic polymer - in order to obtain semipermeable membranes with superior performance to those already known, suitable to biomedical applications. 

Code: PN-II-RU-TD-2007-2. Contract no. 489/01.10.2007.
Project director: Dr. Anca Filimon
Contractor: ICMPP
Period: 2007 - 2009

This project had the objective of establishing the correlation between chemical structure and possible applications of some modified polysulfones obtained by chloromethylation and quaternization.

Code: CEEX 6948/2006. Contract no. 54/2006.
Project director: Dr. Ghiocel Emil  Ioanid
Contractor: ICMPP
Period: 2006 - 2008

Fundamental and applied researches in the field of heritage object conservation. Scientific investigations regarding the elaboration of final conservation treatments with protective role of the movable patrimony objects by the deposition of polymeric films in plasma of high frequency.

Code: PN-III-P1-1.1-PD-2019-1182, Contract: PD 197/27.08.2020
Acronim: BioDrugSyst
Project leader: Dr. Craciun Anda-Mihaela
Contract Authority: UEFISCDI
Contractor: ICMPP
Period: 01.09.2020-31.08.2022.

The aim of the project is to obtain chitosan-based formulations for controlled delivery of 5-fluorouracil, designed for local cancer therapy. The hydrogels obtained by the acid condensation of monoaldehyde (P5P) with chitosan will be used as matrices for preparing injectable formulations, by in situ encapsulation of 5-fluorouracil, an anticancer drug. The obtained hydrogels and formulations will be characterized from structural, supramolecular and morphological points of view using adequate equipment. Thixotropic behavior will be monitored by rheological measurements. Also, in vitro studies of enzymatic degradability, biocompatibility, anticancer activity and drug release will be performed. In vivo biocompatibility tests will be achieved by collaboration with “Gr. T. Popa” University.

Code: PN-III-P1-1.1-PD-2019-1021, Contract: PD 204/27.08.2020
Acronim: HIVFight
Project leader: Dr. Daniela Ailincai
Contract Authority: UEFISCDI
Contractor: ICMPP
Period: 01.09.2020-31.08.2022.

The project has as objective the obtaining of chitooligosaccharides based hydrogels for the co-delivery of antiviral and antifungal agents, used in both HIV and HIV associated co-infections treatment. The hydrogels obtained by the acid condensation of chitooligosaccharides with 2-formyl phenyl boronic acid will be used for the encapsulation of tenofovir antiviral drug. The hydrogels and drug delivery systems will be characterized from the structural, supramolecular and morphological points of view using different techniques. Rheological measurements will be used in order to evaluate the thixotropic behavior of the hydrogels, while their biodegradability will be monitored in vitro in the presence of lysozyme.  Last but not least, the antifungal activity and the biocompatibility of the systems will be also evaluated.  

Code: PN-III-P1-1.1-TE-2019-0639, Contract: TE 89/03.09.2020
Acronim: InElPHoPRo
Project leader: Dr. Diana Serbezeanu
Contract Authority: UEFISCDI
Contractor: ICMPP
Period: 15.09.2020-14.09.2022.

The main objective of the proposed project is to design new flame retarded micro- and nano- fibrous membranes based on phosphorus-containing polymer, by electrospinning process. These membranes are intended to be integrated into fireman protection equipment. Phosphorus-containing polymers bearing P atom both in the main chain and/or the side chain will be synthesized by specific methods and then characterized by different techniques. The polymers prepared in the first step of the project will then be processed by solution electrospinning, with the aim to obtain phosphorus-containing membrane with improved characteristics. The electrospinning process parameters will be optimized in order to obtain membranes with “ideal fabric properties”. The obtained micro and nano- fibrous architectures will be characterized from morphological and functional point of view. Innovative fundamental approaches will be applied to design phosphorous-containing membrane having high air permeability (AP), high water vapor transport (WVTR) properties as well as high hydrostatic resistance (HR), as a class of new materials with superior properties regarding the physiological comfort, recommended for development of improved fireman protective clothes.

Code: RO-NO-2019-0540, Contract 14 / 2020
Acronym: STIM4+
Project leader: Dr. Alina Nicolescu
Contract Authority: UEFISCDI
Contractor: ICMPP
Period: 01.09.2020-31.08.2023

The project addresses the thematic area of Biotechnology, more exactly of the key topic Biotechnology for agriculture, aquaculture, forestry and biomass production. The biotechnological solutions which STIM4+ project proposes to develop are intended to compensate the negative effects of the low-input, high-residue sustainable vegetable production systems. These proposed biotechnological solutions are related to the use of plant biostimulants, and especially to the use of the next generation plant biostimulants. The multi-functional plant biostimulants will be included into a glycodinameric, chitosan based bioactive (micro)hydrogel formulation. The bioactive hydrogel is based on an organic plant biostimulants (chitosan), which will be used to generate a biocompatible 3D porous structure, thermo- and pH-responsive and with a hydrophilic – hydrophobic segregation feature. This hydrophilic – hydrophobic segregation (micro)hydrogels will be used for embedding hydrophobic strigolactones, either natural / either (bio)mimetic. New strigolactone mimics will be subjected to spectroscopic studies including multinuclear (1H-, 13C-, 15N-) both 1D and 2D NMR techniques, single crystal X-Ray, High Resolution MS spectrometry, UV spectroscopy. The studies will provide evidences for the structure of new compounds, including complete stereochemistry. The plant biostimulant effect will be confirmed using microtiter plate assays with model plants. Metabolite profiling will be done by HPLC (ICECHIM) and NMR (ICMPP).

Code: PN-III-P1-1.2-PCCDI-2017-0569, Contract 10 / 2018
Acronym: PROSPER
Project leader: Dr. Calin Deleanu
Contract Authority: UEFISCDI
Contractor: ICMPP
Period: 15.03.2018 -30.06.2021

Development of an edible film product designed to increase the shelf life of fruits. The specific objectives are: recovery of chitin from Agaricus bisporus and conversion to chitosan; obtaining films and hydrogels based on chitosan and bioactive monoaldehydes for bio-applications; extending the concept of hydrogel and biodynamic films to complex systems, with practical uses, which encapsulate new bioactive agents, aiming at their synergistic release

Code: ERANET-INCOMERA-2017-BENDIS, Contract 7 / 2018
Acronym: BENDIS
Project leader: Dr. Calin Deleanu
Contract Authority: UEFISCDI
Contractor: ICMPP
Period: 2018-2019

Synthesis and complete NMR characterization of some strigolactone derivatives with biostimulanting activity for plants

Project leader: Dr. Calin Deleanu
Contract Authority: Sindan-Actavis Teva Group.
Contractor: ICMPP
Period: 01.05.2011-01.05.2022. 

Code: PNII-PT-PCCA-2013-4-0791, Contract 74 / 2014
Acronym: ARMOREC
Project leader: Dr. Alina Nicolescu
Contract Authority: UEFISCDI
Contractor: ICMPP
Period: 2014-2017

Development of a chemometric model based on NMR metabolomics that succeeded in separating the samples according to the type of plant material (flower, leaf, stem) and harvesting sites, for Arnica Montana. Development of NMR methods, as an alternative to the chromatographic method, for the determination of the total sequiterpene lactone content in the inflorescence samples, from Arnica Montana.

Code: PN-II-CT-RO-FR-2014-2-0064, Contract 793 / 30.06.2014
Acronym: SENSIRMN
Project leader: Dr. Calin Deleanu
Contract Authority: UEFISCDI
Contractor: ICMPP
Period: 2014-2016

Bilateral project between Université Paris Descartes - Sorbonne Paris Cité, France and „Petru Poni” Institute of Macromolecular Chemistry, Iasi.

Contract Capacitati Modul III, Nr. 685 / 16.04.2013
Acronym: METABOLOM
Project leader: Dr. Calin Deleanu
Contract Authority: UEFISCDI
Contractor: ICMPP
Period: 2013-2014

Bilateral project between Mother and Child Institute from Chisinau, Moldova and „Petru Poni” Institute of Macromolecular Chemistry, Iasi.